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Invokana – Amputation Risks

Invokana (canagliflozin) was approved in 2013 as a treatment for type 2 diabetes.  Invokana works by inhibiting a substance known as SGLT2 (sodium-glucose co-transporter 2), which reabsorbs the majority of glucose in the kidneys.   According to the drug’s manufacturer this increases urinary glucose excretion and improves blood glucose control.

Invokana has the potential to cause a number of serious side effects including amputation.   According to the latest boxed warning for Invokana:

Risk of Lower-Limb Amputation

  • An approximately 2-fold increased risk of lower-limb amputations associated with INVOKANA® was observed in CANVAS and CANVAS-R, two large, randomized, placebo-controlled trials in patients with type 2 diabetes who had established cardiovascular disease (CVD) or were at risk for CVD.
  • Amputations of the toe and midfoot were most frequent; however, amputations involving the leg were also observed. Some patients had multiple amputations, some involving both limbs.

This means that users of Invokana are 200% more likely to experience an amputation. 

If you or a loved one experienced infection, blister, pain, tenderness, sores and/or ulcers of the lower limbs while taking Invokana that progressed to an amputation, this may be related to Invokana use. 

Your time to file a claim may be limited.  We recommend that you contact a lawyer immediately regarding your potential Invokana amputation claim.

If you or a loved one has suffered harm as the result of using a medical device, pharmaceutical drug, or other product, we have the experience to handle your claim. The attorneys at Freedland Harwin Valori, PL, can help you navigate the confusing process and make sure your case gets the attention that it deserves. For more information, or to schedule a free case evaluation with our firm, please call us or contact us online.

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